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Article

Several classical mouse inbred strains, including DBA/2, NOD/Lt, FVB/N, and SJL/J, carry a putative loss-of-function allele of Gpr84.

The Journal of heredity - 1 Jan 2000

Perez Carlos J, Dumas Aline, Vallières Luc, Guénet Jean-Louis, Benavides Fernando

Abstract excerpt

G protein-coupled receptor 84 (GPR84) is a 7-transmembrane protein expressed on myeloid cells that can bind to medium-chain free fatty acids in vitro. Here, we report the discovery of a 2-bp frameshift deletion in the second exon of the Gpr84 gene in several classical mouse inbred strains. This deletion generates a premature stop codon predicted to result in a truncated protein lacking the transmembrane domains...

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Identifiers

PMID: 23616478
DOI: 10.1093/jhered/est023
PMCID: PMC3954108

Genes

GPR84

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