Molecular analysis of genetic differences among inbred mouse strains controlling tissue expression pattern of alcohol dehydrogenase 4.

doi:10.1016/s0378-1119(01)00409-7

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Article

Molecular analysis of genetic differences among inbred mouse strains controlling tissue expression pattern of alcohol dehydrogenase 4.

Gene - 18 Apr 2001

Dolney D E, Szalai G, Duester G, Felder M R

Abstract excerpt

The ADH gene family in vertebrates is composed of at least seven distinct classes based upon sequence comparisons and enzyme properties. The Adh4 gene product may play an important role in differentiation and development because of its capacity to metabolize retinol to retinoic acid. Allelic gene differences exist among inbred mouse strains which control structure and tissue-specific regulation of Adh4. C57BL/6...

Topics

Alcohol Dehydrogenase
Alleles
Alternative Splicing
Amino Acid Sequence
Animals
Base Sequence
Blotting, Northern
DNA, Complementary
Female
Gene Expression Regulation, Enzymologic
Isoenzymes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Mice

Mice, Inbred C3H

Mice, Inbred Strains

Molecular Sequence Data

Poly A

Polymerase Chain Reaction

Source

Open in PubMed

Identifiers

PMID: 11313141
DOI: 10.1016/s0378-1119(01)00409-7

Genes

ADH4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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