Article
Ultra-high field NMR studies of antibody binding and site-specific phosphorylation of alpha-synuclein.
Biochemical and biophysical research communications - 23 Nov 2007
Sasakawa Hiroaki, Sakata Eri, Yamaguchi Yoshiki, Masuda Masami, Mori Tetsuya, Kurimoto Eiji, Iguchi Takeshi, Hisanaga Shin-ichi, Iwatsubo Takeshi, Hasegawa Masato, Kato Koichi
Abstract excerpt
Although biological importance of intrinsically disordered proteins is becoming recognized, NMR analyses of this class of proteins remain as tasks with more challenge because of poor chemical shift dispersion. It is expected that ultra-high field NMR spectroscopy offers improved resolution to cope with this difficulty. Here, we report an ultra-high field NMR study of alpha-synuclein, an intrinsically disordered...
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