Article
Genome-wide association studies in atherosclerosis.
Current atherosclerosis reports - 1 Jun 2011
Sivapalaratnam S, Motazacker M M, Maiwald S, Hovingh G K, Kastelein J J P, Levi M, Trip M D, Dallinga-Thie G M
Abstract excerpt
Cardiovascular disease remains the major cause of worldwide morbidity and mortality. Its pathophysiology is complex and multifactorial. Because the phenotype of cardiovascular disease often shows a marked heritable pattern, it is likely that genetic factors play an important role. In recent years, large genome-wide association studies have been conducted to decipher the molecular mechanisms underlying this...
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