Article
Common genetic variants and subclinical atherosclerosis: The Multi-Ethnic Study of Atherosclerosis (MESA).
Atherosclerosis - 1 Feb 2016
Vargas Jose D, Manichaikul Ani, Wang Xin-Qun, Rich Stephen S, Rotter Jerome I, Post Wendy S, Polak Joseph F, Budoff Matthew J, Bluemke David A
Abstract excerpt
BACKGROUND AND AIMS: Subclinical atherosclerosis (sCVD), measured by coronary artery calcium (CAC) and carotid intima media thickness (CIMT) is associated with cardiovascular disease (CVD). Genome-Wide Association Studies (GWAS) of sCVD and CVD have focused primarily on Caucasian populations. We hypothesized that these associations may differ in populations from distinct genetic backgrounds. METHODS: The...
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