Article
Autosomal genome-wide scan for coronary artery calcification loci in sibships at high risk for hypertension.
Arteriosclerosis, thrombosis, and vascular biology - 1 Mar 2002
Lange Leslie A, Lange Ethan M, Bielak Lawrence F, Langefeld Carl D, Kardia Sharon L, Royston Patrick, Turner Stephen T, Sheedy Patrick F, Boerwinkle Eric, Peyser Patricia A
Abstract excerpt
Coronary artery disease (CAD) is the leading cause of mortality in the developed world. Although several CAD risk factors, including measures of lipid metabolism, obesity, and blood pressure, have a genetic basis, many genes for CAD susceptibility have yet to be identified. Coronary atherosclerosis is the major cause of CAD, but many with coronary atherosclerosis lack symptoms. Thus, a major limitation of using...
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