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Article

Genetic and environmental contributions to atherosclerosis phenotypes in men and women: heritability of carotid intima-media thickness in the Framingham Heart Study.

Stroke - 1 Feb 2003

Fox Caroline S, Polak Joseph F, Chazaro Irmarie, Cupples Adrienne, Wolf Philip A, D'Agostino Ralph A, O'Donnell Christopher J

Abstract excerpt

BACKGROUND AND PURPOSE: Carotid intima-media thickness (IMT) is a quantitative measure of subclinical atherosclerosis that is predictive of subsequent myocardial infarction and stroke. There is controversy regarding the proportion of variability in IMT explained by genetic factors. Thus, it is uncertain whether carotid IMT is a heritable trait that can be used in genetic studies. METHODS: From 1996 to 1998, we...

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PMID: 12574549
DOI: 10.1161/01.str.0000048214.56981.6f

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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