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Article

Phosphorylation of steroidogenic factor 1 is mediated by cyclin-dependent kinase 7.

Molecular endocrinology (Baltimore, Md.) - 1 Jan 2008

Lewis Aurélia E, Rusten Marte, Hoivik Erling A, Vikse Elisabeth L, Hansson Magnus L, Wallberg Annika E, Bakke Marit

Abstract excerpt

The nuclear receptor steroidogenic factor-1 (SF1) is critical for development and function of steroidogenic tissues. Posttranslational modifications are known to influence the transcriptional capacity of SF1, and it was previously demonstrated that serine 203 is phosphorylated. In this paper we report that serine 203 is phosphorylated by a cyclin-dependent kinase 7 (CDK7)-mediated process. As part of the...

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Source

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Identifiers

PMID: 17901130
DOI: 10.1210/me.2006-0478
PMCID: PMC5419630

Genes

CDK7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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