Article
Regional gray matter volume abnormalities in the at risk mental state.
Biological psychiatry - 15 May 2007
Borgwardt Stefan J, Riecher-Rössler Anita, Dazzan Paola, Chitnis Xavier, Aston Jacqueline, Drewe Margret, Gschwandtner Ute, Haller Sven, Pflüger Marlon, Rechsteiner Evelyne, D'Souza Marcus, Stieglitz Rolf-Dieter, Radü Ernst-Wilhelm, McGuire Philip K
Abstract excerpt
BACKGROUND: Individuals with an At Risk Mental State (ARMS) have a very high risk of developing a psychotic disorder but the basis of this risk is unclear. We addressed this issue by studying gray matter volume in this group with magnetic resonance imaging (MRI). METHODS: Thirty-five individuals with an ARMS, 25 patients with first episode schizophrenia, and 22 healthy volunteers were studied using a 1.5T MRI...
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