Article
Age-related brain structural alterations as an intermediate phenotype of psychosis.
Journal of psychiatry & neuroscience : JPN - 1 Sept 2017
Dukart Juergen, Smieskova Renata, Harrisberger Fabienne, Lenz Claudia, Schmidt André, Walter Anna, Huber Christian, Riecher-Rössler Anita, Simon Andor, Lang Undine E, Fusar-Poli Paolo, Borgwardt Stefan
Abstract excerpt
BACKGROUND: There is only limited agreement with respect to location, directionality and functional implications of brain structural alterations observed in patients with schizophrenia. Additionally, their link to occurrence of psychotic symptoms remains unclear. A viable way of addressing these questions is to examine populations in an at-risk mental state (ARMS) before the transition to psychosis. METHODS: We...
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