Article

Ultra-high field imaging of hippocampal neuroanatomy in first episode psychosis demonstrates receptor-specific morphometric patterning

2019-11-04

Abstract excerpt

<h4>Objective</h4> The hippocampus is considered a putative marker in schizophrenia with early volume deficits of select subfields. Certain subregions are thought to be more vulnerable due to a glutamate-driven mechanism of excitotoxicity, hypermetabolism, and then degeneration. Here, we explored whether hippocampal anomalies in first-episode psychosis (FEP) correlate with glutamate receptor density via a seroton...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 620b2139-f7be-5589-ba4d-06d77e0445be
DOI: 10.1101/829630

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Ultra-high field imaging of hippocampal neuroanatomy in first episode psychosis demonstrates receptor-specific morphometric patterningDOI 10.1101/829630Read

Molecular and micro-architectural mapping of gray matter alterations in psychosisSemantic proximity Read

Subtyping psychotic disorders using a data-driven approach reveals divergent cortical and cellular signaturesSemantic proximity Read

GABA<sub>A</sub>receptor availability in clinical high-risk and first-episode psychosis: a [<sup>11</sup>C]Ro15-4513 positron emission tomography studySemantic proximity Read

Transcriptomics and proteomics of projection neurons in a circuit linking hippocampus with dorsolateral prefrontal cortex in the human brainSemantic proximity Read

Network-based Molecular Constraints on in vivo Synaptic Density Alterations in SchizophreniaSemantic proximity Read

Normative Modelling of Molecular-based Functional Neurocircuits Captures Clinical Heterogeneity Transdiagnostically in Neuropsychiatric PatientsSemantic proximity Read

Mapping Neurochemical Signatures onto Brain Structure for Neurotransmitter-Informed Discrimination of Schizophrenia Patients from Healthy ControlsSemantic proximity Read

Hippocampal gray matter volume alterations in patients with first-episode and recurrent major depressive disorder and their associations with gene profilesSemantic proximity Read

Neurochemical and molecular characteristics of altered brain functional activity in the anti-NMDAR encephalitisSemantic proximity Read

InSpectro-Gadget: A tool for estimating neurotransmitter and neuromodulator receptor distributions for MRS voxelsSemantic proximity Read

Excitatory inhibitory imbalance underlies hippocampal atrophy in individuals with 22q11.2 Deletion Syndrome with psychotic symptomsSemantic proximity Read

Differential effects of illness and antipsychotics on cortical thinning in first episode psychosisSemantic proximity Read