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Article

Local delivery of anti-monocyte chemoattractant protein-1 by gene-eluting stents attenuates in-stent stenosis in rabbits and monkeys.

Arteriosclerosis, thrombosis, and vascular biology - 1 Dec 2007

Egashira Kensuke, Nakano Kaku, Ohtani Kisho, Funakoshi Kouta, Zhao Gang, Ihara Yoshiko, Koga Jun-Ichiro, Kimura Satoshi, Tominaga Ryuji, Sunagawa Kenji

Abstract excerpt

OBJECTIVE: We have previously shown that the intramuscular transfer of the anti-monocyte chemoattractant protein-1 (MCP-1) gene (called 7ND) is able to prevent experimental restenosis. The aim of this study was to determine the in vivo efficacy and safety of local delivery of 7ND gene via the gene-eluting stent in reducing in-stent neointima formation in rabbits and in cynomolgus monkeys. METHODS AND RESULTS: We...

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PMID: 17885211
DOI: 10.1161/ATVBAHA.107.154609

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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