Article
Inhibition of neointimal formation in porcine coronary artery by a Ras mutant.
The Journal of surgical research - 1 Jul 2001
Wu C H, Lin C S, Hung J S, Wu C J, Lo P H, Jin G, Shyy Y J, Mao S J, Chien S
Abstract excerpt
BACKGROUND: Therapeutic approaches to reduce the neointimal formation caused by balloon injury have been focused mainly on experimental models of restenosis in the rat carotid artery. However, restenosis in rat carotid artery may not replicate the coronary arterial responses to injury in larger animals and humans. METHODS: In this study, we used pig coronary arteries as an animal model to evaluate the preventive...
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