Article
Transfection with a dominant-negative inhibitor of monocyte chemoattractant protein-1 gene improves cardiac function after 6 hours of cold preservation.
Circulation - 9 Sept 2003
Kajihara Noriyoshi, Morita Shigeki, Nishida Takahiro, Tatewaki Hideki, Eto Masataka, Egashira Kensuke, Yasui Hisataka
Abstract excerpt
BACKGROUND: Monocyte chemoattractant protein-1 (MCP-1), a potent chemotactic factor for monocytes, is induced during ischemia-reperfusion. As monocytes might play an important causative role in reperfusion injury, we investigated if inhibition of monocyte activation could attenuate ischemia-reper...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.