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Article

Anti-monocyte chemoattractant protein-1 gene therapy inhibits restenotic changes (neointimal hyperplasia) after balloon injury in rats and monkeys.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Nov 2002

Usui Makoto, Egashira Kensuke, Ohtani Kisho, Kataoka Chu, Ishibashi Minako, Hiasa Ken-ichi, Katoh Makoto, Zhao Qingwei, Kitamoto Shiro, Takeshita Akira

Abstract excerpt

Prevention of restenosis after coronary intervention is a major clinical challenge, which highlights the need of new therapeutic options. Vascular injury may involve inflammatory responses that accelerate the recruitment and activation of monocytes through the activation of chemotactic factors, including monocyte chemoattractant protein-1 (MCP-1). However, there is no definitive evidence supporting the role of...

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Identifiers

PMID: 12223446
DOI: 10.1096/fj.02-0094fje

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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