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Article

Local Gene Transfer of phVEGF-2 Plasmid by Gene-Eluting Stents

22 Jun 2004

Abstract excerpt

BACKGROUND: Drug-eluting stents represent a useful strategy for the prevention of restenosis using various antiproliferative drugs. These strategies share the liability of impairing endothelial recovery, thereby altering the natural biology of the vessel wall and increasing the associated risk of stent thrombosis. Accordingly, we tested the hypothesis that local delivery via gene-eluting stent of naked plasmid...

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PMID: 15210598
DOI: 10.1161/01.cir.0000133324.38115.0a

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