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Article

Interactions between childhood maltreatment and brain-derived neurotrophic factor and serotonin transporter polymorphisms on depression symptoms.

Psychiatry research - 30 Sept 2015

Harkness Kate L, Strauss John, Michael Bagby R, Stewart Jeremy G, Larocque Cherie, Mazurka Raegan, Ravindran Arun, Wynne-Edwards Katherine E, Rector Neil A, Kennedy James

Abstract excerpt

This study represents the first replication of the BDNF Val66Met ⁎ 5-HTTLPR ⁎ childhood maltreatment effect on self-reported depression symptoms using a rigorous maltreatment interview. Participants included a community sample of 339 adolescents/young adults (age 12-33; 265 female). In the context of childhood neglect, among BDNF Met-carriers, s-allele carriers of 5-HTTLPR reported significantly higher depression...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Serotonin Plasma Membrane Transport Proteins

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Source

Identifiers

PMID: 26070769
DOI: 10.1016/j.psychres.2015.04.040

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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