Article
Hypoxia and reoxygenation: a pressure for mutant p53 cell selection and tumour progression.
Bulletin of mathematical biology - 1 Jul 1999
Thompson K E, Royds J A
Abstract excerpt
Recent findings indicate that in a hypoxic environment, oncogenically transformed cells with a mutant form of the tumour suppressor gene p53 may have a survival advantage over similar cells with wild-type p53. This is because the extent of hypoxia-induced apoptosis has been observed to diminish w...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
