Response of tumour cells to hypoxia: role of p53 and NFkB.

doi:10.1136/mp.51.2.55

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Article

Response of tumour cells to hypoxia: role of p53 and NFkB.

Molecular pathology : MP - 1 Apr 1998

Royds J A, Dower S K, Qwarnstrom E E, Lewis C E

Abstract excerpt

Hypoxia is present in several areas of malignant tumours and is thought to result from an inadequate rate of tumour angiogenesis, vascular collapse, or both. The presence and extent of these hypoxic tumour microenvironments have recently been shown to influence tumour progression by regulating bo...

Topics

Genes, p53
Humans
Hypoxia
Mutation
NF-kappa B
Neoplasms
Neovascularization, Pathologic

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