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Article

Cancer cells surviving hypoxia obtain hypoxia resistance and maintain anti‐apoptotic potential under reoxygenation

1 Feb 2001

Abstract excerpt

In solid tumors hypoxia and reoxygenation may be important factors in secondary expansion after anti-cancer therapy. Our study examined the effect of hypoxia and reoxygenation on the apoptotic potential of cancer cells. Four experimental groups were studied using a human colorectal cancer cell line (HCT116) that is apoptosis-competent in conventional culture: (1) sham, cells grown under conventional conditions;...

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PMID: 11169954
DOI: 10.1002/1097-0215(200002)9999:9999<::aid-ijc1064>3.0.co;2-p

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