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Article

A role for 12/15 lipoxygenase in the amyloid beta precursor protein metabolism.

Journal of neurochemistry - 1 Oct 2007

Succol Francesca, Praticò Domenico

Abstract excerpt

12/15 Lipoxygenase (12/15LO) protein levels and activity are increased in pathologically affected regions of Alzheimer's disease (AD) brains, compared with controls. Its metabolic products are elevated in cerebrospinal fluid of patients with AD and individuals with mild cognitive impairment, sugg...

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Source

Identifiers

PMID: 17877641
DOI: 10.1111/j.1471-4159.2007.04742.x

Genes

APP
ADAM10

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17877641-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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