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15-Lipoxygenase and its metabolites in the pathogenesis of breast cancer: A double-edged sword

27 Nov 2021

Abstract excerpt

15-lipoxygenase is one of the key enzymes for the metabolism of unsaturated fatty acids that its manipulation has been proposed recently as a new molecular target for regulating cancer cell growth. Aberrant expression of 15-lipoxygenase enzyme seems to play an indicative role in the pathology of different cancer types, tumor progression, metastasis, or apoptosis. Based on the fact that breast cancer is one of the...

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PMID: 34838055
DOI: 10.1186/s12944-021-01599-2

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