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Article

Complement Factor H polymorphism Y402H associates with inflammation, visual acuity, and cardiovascular mortality in the elderly population at large.

Experimental gerontology - 1 Nov 2007

Mooijaart Simon P, Koeijvoets Kristel M C, Sijbrands Eric J G, Daha Mohamed R, Westendorp Rudi G J

Abstract excerpt

The haplotype tagging Y402H polymorphism in the Complement Factor H gene (CFH) has consistently been associated with age-related macular degeneration, whereas conflicting results have been reported on its relationship with cardiovascular disease. CFH plays a role in inflammation, which is causal to both diseases and both are highly prevalent in old age. Therefore, we investigated whether or not Y402H associated...

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Identifiers

PMID: 17869048
DOI: 10.1016/j.exger.2007.08.001

Genes

CFH

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Complement Factor H polymorphism Y402H associates with inflammation, visual acuity, and cardiovascular mortality in the elderly population at large.PMID 17869048Read ↗

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