Article
Inhibition of cortical astrocyte differentiation by Hes6 requires amino- and carboxy-terminal motifs important for dimerization and phosphorylation.
Journal of neurochemistry - 1 Dec 2007
Belanger-Jasmin Stephanie, Llamosas Estelle, Tang Yeman, Joachim Kerline, Osiceanu Ana-Maria, Jhas Sumit, Stifani Stefano
Abstract excerpt
Hairy/Enhancer of split (Hes) 6 is a basic helix-loop-helix protein that interacts with the transcriptional co-repressor, Groucho, and antagonizes the neural functions of the Notch pathway. More specifically, mouse Hes6 regulates cerebral corticogenesis by promoting neurogenesis and suppressing a...
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