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Article

Sumoylation differentially regulates Goosecoid-mediated transcriptional repression.

Experimental cell research - 15 Apr 2008

Izzi Luisa, Narimatsu Masahiro, Attisano Liliana

Abstract excerpt

Goosecoid (Gsc), a paired-like homeobox gene expressed in the vertebrate organizer, functions as a transcriptional repressor either by direct DNA binding to paired TAAT homeodomain sites or through recruitment by the forkhead/winged helix transcription factor Foxh1. Here, we report that Gsc is post-translationally modified by small ubiquitin-like modifier proteins (SUMO). Members of the PIAS family of proteins...

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Identifiers

PMID: 18336814
DOI: 10.1016/j.yexcr.2008.01.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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