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Article

The restriction of zoonotic PERV transmission by human APOBEC3G.

PloS one - 12 Sept 2007

Jónsson Stefán R, LaRue Rebecca S, Stenglein Mark D, Fahrenkrug Scott C, Andrésdóttir Valgerdur, Harris Reuben S

Abstract excerpt

The human APOBEC3G protein is an innate anti-viral factor that can dominantly inhibit the replication of some endogenous and exogenous retroviruses. The prospects of purposefully harnessing such an anti-viral defense are under investigation. Here, long-term co-culture experiments were used to show that porcine endogenous retrovirus (PERV) transmission from pig to human cells is reduced to nearly undetectable...

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Source

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Identifiers

PMID: 17849022
DOI: 10.1371/journal.pone.0000893
PMCID: PMC1963317

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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