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Chapter 5: Strategies to prevent transmission of porcine endogenous retroviruses

1 Jul 2009

Abstract excerpt

Xenotransplantation using porcine cells, tissues, or organs may offer a potential solution for the shortage of allogeneic human organs. Prior to the clinical use of porcine xenotransplants, three main hurdles must be overcome: immunologic rejection, physiologic incompatibility, and risk of transmission of porcine pathogens. Designated pathogen-free breeding of pigs can prevent transmission of most porcine...

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PMID: 19799764
DOI: 10.1111/j.1399-3089.2009.00544.x

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