Elimination of porcine endogenous retroviruses from pig cells

Abstract excerpt

Recently, a group of scientists under the guidance of George Church at Harvard Medical School published in “Science” that it succeeded to inactivate 62 porcine endogenous retroviruses (PERVs) in the genome of a pig cell line 1. At present, PERVs still represent the main microbiological risk for xenotransplantation. Virus-encoding gene segments (so-called proviruses) are integrated in the genome of all pigs, and...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Animal Genetics and Reproduction
• Share to Virus-based gene therapy research
• Share to Xenotransplantation and immune response