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Article

Analysis of PERV-C superinfection resistance using HA-tagged viruses.

Retrovirology - 21 Aug 2023

Flecks Merle, Fischer Nicole, Krijnse Locker Jacomina, Tönjes Ralf R, Godehardt Antonia W

Abstract excerpt

BACKGROUND: Using pigs as organ donors has advanced xenotransplantation to the point that it is almost ready for clinical use. However, there is still a zoonotic risk associated with xenotransplantation, and the potential transmission of porcine endogenous retroviruses needs to be surveyed. Despite significant attempts to eliminate this risk, by the selection of PERV-C free pigs with low expression of PERV-A, -B,...

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PMID: 37605152
DOI: 10.1186/s12977-023-00630-x
PMCID: PMC10440901

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