Article

Extensive Mammalian Germline Genome Engineering

2019-12-19

Abstract excerpt

Xenotransplantation, specifically the use of porcine organs for human transplantation, has long been sought after as an alternative for patients suffering from organ failure. However, clinical application of this approach has been impeded by two main hurdles: 1) risk of transmission of porcine endogenous retroviruses (PERVs) and 2) molecular incompatibilities between donor pigs and humans which culminate in reject...

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Literature Corpus work: 8d9b8569-7e96-5720-8112-9762be4d8446
DOI: 10.1101/2019.12.17.876862

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