Article
The Mcf1 toxin induces apoptosis via the mitochondrial pathway and apoptosis is attenuated by mutation of the BH3-like domain.
Cellular microbiology - 1 Oct 2007
Dowling Andrea J, Waterfield Nicholas R, Hares Michelle C, Le Goff Gaëlle, Streuli Charles H, ffrench-Constant Richard H
Abstract excerpt
Photorhabdus are Gram-negative, nematode-vectored bacteria that produce toxins to kill their insect hosts. The expression of one of these, Makes caterpillars floppy 1 (Mcf1), is sufficient to allow Escherichia coli to survive within, and kill, caterpillars which are otherwise able to clear E. col...
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