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Article

The Bax inhibitor MrBI-1 regulates heat tolerance, apoptotic-like cell death, and virulence in Metarhizium robertsii.

Scientific reports - 29 May 2015

Chen Yixiong, Duan Zhibing, Chen Peilin, Shang Yanfang, Wang Chengshu

Abstract excerpt

Bax inhibitor 1 (BI-1) is a highly conserved protein originally identified as a suppressor of the proapoptotic protein Bax to inhibit cell death in animals and plants. The orthologs of BI-1 are widely distributed in filamentous fungi but their functions remain largely unknown. Herein, we report the identification and characterizations of MrBI-1, an ortholog of BI-1, in the entomopathogenic fungus Metarhizium...

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Identifiers

PMID: 26023866
DOI: 10.1038/srep10625
PMCID: PMC4448503

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