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Article

In vivo induction of apoptosis correlating with reduced infectivity during baculovirus infection.

Journal of virology - 1 Feb 2003

Clarke Thomas E, Clem Rollie J

Abstract excerpt

Spodoptera frugiperda caterpillars were infected with a mutant of Autographa californica M nucleopolyhedrovirus lacking the antiapoptotic p35 gene. Viral infectivity, replication, and spread were substantially reduced compared to that of a control revertant virus. Terminal deoxynucleotidyltransferase-mediated dUTP-biotin nick end labeling confirmed that apoptosis occurred in mutant-infected caterpillars, thus...

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Identifiers

PMID: 12525657
DOI: 10.1128/jvi.77.3.2227-2232.2003
PMCID: PMC140947

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Source receipt: pubmed, retrieved 7 Sept 2026.

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