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Article

Effects of mutating α-tubulin lysine 40 on sensory dendrite development.

Journal of cell science - 15 Dec 2017

Jenkins Brian V, Saunders Harriet A J, Record Helena L, Johnson-Schlitz Dena M, Wildonger Jill

Abstract excerpt

Microtubules are essential for neuronal structure and function. Axonal and dendritic microtubules are enriched in post-translational modifications that impact microtubule dynamics, transport and microtubule-associated proteins. Acetylation of α-tubulin lysine 40 (K40) is a prominent and conserved modification of neuronal microtubules. However, the cellular role of microtubule acetylation remains controversial. To...

Topics

Acetylation
Animals
Dendrites
Drosophila melanogaster
Lysine
Microtubules
Morphogenesis
Mutation
Neurogenesis
Protein Processing, Post-Translational
Sensory Receptor Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tubulin

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Identifiers

PMID: 29122984
DOI: 10.1242/jcs.210203
PMCID: PMC5769580

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