Article
Flagellar regeneration requires cytoplasmic microtubule depolymerization and kinesin-13.
Journal of cell science - 15 Mar 2013
Wang Liang, Piao Tian, Cao Muqing, Qin Tao, Huang Lei, Deng Haiteng, Mao Tonglin, Pan Junmin
Abstract excerpt
In ciliated cells, two types of microtubules can be categorized: cytoplasmic and axonemal. It has been shown that axonemal tubulins come from a 'cytoplasmic pool' during cilia regeneration. However, the identity and regulation of this 'pool' is not understood. Previously, we have shown that Chlamydomonas kinesin-13 (CrKin13) is phosphorylated during flagellar regeneration, and required for proper flagellar...
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