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Article

Evidence for transgenerational transmission of epigenetic tumor susceptibility in Drosophila.

PLoS genetics - 1 Sept 2007

Xing Yalan, Shi Song, Le Long, Lee Crystal A, Silver-Morse Louise, Li Willis X

Abstract excerpt

Transgenerational epigenetic inheritance results from incomplete erasure of parental epigenetic marks during epigenetic reprogramming at fertilization. The significance of this phenomenon, and the mechanism by which it occurs, remains obscure. Here, we show that genetic mutations in Drosophila may cause epigenetic alterations that, when inherited, influence tumor susceptibility of the offspring. We found that...

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Identifiers

PMID: 17845077
DOI: 10.1371/journal.pgen.0030151
PMCID: PMC1971119

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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