The Drosophila Tumorous-lethal hematopoietic oncogene is a dominant mutation in the hopscotch locus.

doi:10.1007/BF00279527

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Article

The Drosophila Tumorous-lethal hematopoietic oncogene is a dominant mutation in the hopscotch locus.

Molecular & general genetics : MGG - 1 Apr 1993

Hanratty W P, Dearolf C R

Abstract excerpt

The Drosophila Tumorous-lethal (Tum-l) mutation acts as an activated oncogene, causing hematopoietic neoplasms, overproliferation, and premature differentiation. Tum-l is a dominant mutation in the hopscotch (hop) locus, which is required for cell division and for proper embryonic segmentation. T...

Topics

Animals
Crosses, Genetic
Drosophila melanogaster
Female
Genes, Dominant
Genes, Lethal
Genetic Complementation Test
Male
Mutation
Oncogenes
Recombination, Genetic
Temperature
Time Factors

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