Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Etiologic impact of known cancer susceptibility genes.

Mutation research - 1 Jan 2000

Hemminki Kari, Försti Asta, Lorenzo Bermejo Justo

Abstract excerpt

The impact of a gene variant on the population burden of cancer can be measured by the population attributable fraction (PAF), which depends on the risk conferred by the variant, genotype relative risk (GRR), the frequency of the variant in the population and the mode of inheritance. PAF defines...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Frequency
Share to VHL gene
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Mutation

Share to Neoplasms

Share to Risk Factors

Source

Identifiers

PMID: 17827054
DOI: 10.1016/j.mrrev.2007.07.001

Genes

VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17827054-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Etiologic impact of known cancer susceptibility genes.PMID 17827054Read ↗

New cancer susceptibility loci: population and familial risks.Semantic proximity Read ↗

Inherited Susceptibility to Cancer: Past, Present and Future.Semantic proximity Read ↗

Inherited susceptibility to common cancers.Semantic proximity Read ↗

A compendium of genome-wide associations for cancer: critical synopsis and reappraisal.Semantic proximity Read ↗

Harvard report on cancer prevention. Causes of human cancer. Genetic susceptibility.Semantic proximity Read ↗

Systematic analysis of disease-linked rare germline variants reveals new classes of cancer predisposing genesSemantic proximity Read ↗

Hereditary Decreased Cancer Risk: Reality or Mirage? A ReviewSemantic proximity Read ↗

Cancer genes and risk assessment.Semantic proximity Read ↗

Rare genetic variants and the risk of cancer.Semantic proximity Read ↗

Genetic architecture of cancer and other complex diseases: lessons learned and future directions.Semantic proximity Read ↗

Gene-level heritability analysis explains the polygenic architecture of cancerSemantic proximity Read ↗

Assessment of Polygenic Architecture and Risk Prediction based on Common Variants Across Fourteen CancersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.