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Article

New cancer susceptibility loci: population and familial risks.

International journal of cancer - 1 Oct 2008

Hemminki Kari, Försti Asta, Lorenzo Bermejo Justo

Abstract excerpt

The recent large genotyping studies have identified a new repertoire of cancer susceptibility genes and loci which are characterized by common risk alleles and low relative risks. Because of these properties, these loci explain a much larger proportion of the etiology of the particular cancers, described by the population attributable fraction (PAF), than of their familial risks (FRRs). For breast cancer, the 9...

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PMID: 18623115
DOI: 10.1002/ijc.23702

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