Article
The effect of novel nitrogen-rich plasma polymer coatings on the phenotypic profile of notochordal cells.
Biomedical engineering online - 6 Sept 2007
Mwale Fackson, Wang Hong Tian, Petit Alain, Girard-Lauriault Pierre-Luc, Hunter Christopher J, Ouellet Jean A, Wertheimer Michael R, Antoniou John
Abstract excerpt
BACKGROUND: The loss of the notochordal cells from the nucleus pulposus is associated with ageing and disc degeneration. However, understanding the mechanisms responsible for the loss of these cells has been hampered in part due to the difficulty of culturing and maintaining their phenotype. Furthermore, little is known about the influence of the substratum on the molecular markers of notochordal cells. METHODS:...
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