Article
Same-species phenotypic comparison of notochordal and mature nucleus pulposus cells.
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society - 1 Sept 2015
Saggese Taryn, Redey Prutha, McGlashan Susan R
Abstract excerpt
PURPOSE: The ratio of notochordal (NC) cells to mature nucleus pulposus (MNP) cells in the nucleus pulposus varies with species, age and health. Studies suggest that loss of NC cells is a key component of intervertebral disc degeneration. However, few studies have examined the phenotypes of these two cell populations. Therefore, this study aimed to isolate NC and MNP cells from the same intervertebral disc and...
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