Article
Dapsone N-acetylation, metoprolol alpha-hydroxylation, and S-mephenytoin 4-hydroxylation polymorphisms in an Indonesian population: a cocktail and extended phenotyping assessment trial.
Clinical pharmacology and therapeutics - 1 Aug 1994
Setiabudy R, Kusaka M, Chiba K, Darmansjah I, Ishizaki T
Abstract excerpt
We examined dapsone N-acetylation and metoprolol alpha-hydroxylation and S-mephenytoin 4-hydroxylation phenotypings using the respective test probes (dapsone and racemic metoprolol and mephenytoin) administered separately and in a cocktail manner to an Indonesian subject group (n = 30). After asc...
Topics
- Acetylation
- Adolescent
- Adult
- Asian People
- China
- Dapsone
- Female
- Humans
- Hydroxylation
- Indonesia
- Japan
- Male
- Mephenytoin
- Metoprolol
- Middle Aged
- Phenotype
- Polymorphism, Genetic