Article
Glucose-6-phosphate dehydrogenase deficiency and sulfadimidin acetylation phenotypes in Egyptian oases.
Biochemical genetics - 1 Apr 1992
Hussein L, Yamamah G, Saleh A
Abstract excerpt
Screening of 1315 males from two Egyptian oases for glucose-6-phosphate dehydrogenase deficiency (G-6PD) found an incidence of 5.9%. The rate of acetylation of sulfadimidin was also studied, and a bimodal distribution was found with 73% rapid acetylators. There is a correlation between high frequency of G-6PD deficiency and high frequency of slow acetylation rate.
Topics
- Acetylation
- Child
- Child, Preschool
- Egypt
- Gene Frequency
- Glucosephosphate Dehydrogenase Deficiency
- Humans
- Infant
- Infant, Newborn
- Male
- Phenotype
- Polymorphism, Genetic