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Article

Tumor suppressor CYLD regulates JNK-induced cell death in Drosophila.

Developmental cell - 1 Sept 2007

Xue Lei, Igaki Tatsushi, Kuranaga Erina, Kanda Hiroshi, Miura Masayuki, Xu Tian

Abstract excerpt

CYLD encodes a tumor suppressor that is mutated in familial cylindromatosis. Despite biochemical and cell culture studies, the physiological functions of CYLD in animal development and tumorigenesis remain poorly understood. To address these questions, we generated Drosophila CYLD (dCYLD) mutant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17765686
DOI: 10.1016/j.devcel.2007.07.012

Genes

CYLD
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17765686-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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