Article
Tandem duplications of MLL and FLT3 are correlated with poor prognoses in pediatric acute myeloid leukemia: a study of the Japanese childhood AML Cooperative Study Group.
Pediatric blood & cancer - 1 Feb 2008
Shimada Akira, Taki Tomohiko, Tabuchi Ken, Taketani Takeshi, Hanada Ryoji, Tawa Akio, Tsuchida Masahiro, Horibe Keizo, Tsukimoto Ichiro, Hayashi Yasuhide
Abstract excerpt
BACKGROUND: Mixed-lineage leukemia (MLL)-partial tandem duplication (PTD) is associated with poor prognosis in adult acute myeloid leukemia (AML), but its relationship to pediatric AML is unknown. PROCEDURE: One hundred fifty-eight newly diagnosed AML patients, including 13 FAB-M3 and 10 Down syndrome (DS) patients, who were treated on the Japanese Childhood AML Cooperative Treatment Protocol AML 99 were analyzed...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.