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Article

The MLL partial tandem duplication in acute myeloid leukaemia.

British journal of haematology - 1 Nov 2006

Basecke Jorg, Whelan Jarrett T, Griesinger Frank, Bertrand Fred E

Abstract excerpt

Mixed lineage leukaemia gene-partial tandem duplications (MLL-PTD) characterise acute myeloid leukaemia (AML) with trisomy 11 and AML with a normal karyotype. MLL-PTD confer a worse prognosis with shortened overall and event free survival in childhood and adult AML. In spite of these clinical observations, the leukaemogenic mechanism has, so far, not been determined. This review summarises clinical studies on...

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Share to Chromosomes, Human, Pair 11
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Histone-Lysine N-Methyltransferase

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Source

Identifiers

PMID: 16965385
DOI: 10.1111/j.1365-2141.2006.06301.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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