Article
A coding polymorphism of the kallikrein 1 gene is associated with essential hypertension: a tagging SNP-based association study in a Chinese Han population.
Journal of hypertension - 1 Sept 2007
Zhao Weiyan, Wang Laiyuan, Lu Xiangfeng, Yang Wei, Huang Jianfeng, Chen Shufeng, Gu Dongfeng
Abstract excerpt
OBJECTIVE: The aim of this study was to investigate the association between common variants in the human tissue kallikrein 1 (KLK1) gene and susceptibility to essential hypertension in Chinese Han. METHODS: A tagging single nucleotide polymorphism (tSNP) approach was used for a case-control study in 2411 patients with essential hypertension and 2348 controls. All DNA samples and clinical data were collected from...
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