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Article

Verification of 525 coding SNPs in 179 hypertension candidate genes in the Japanese population: identification of 159 SNPs in 93 genes.

Journal of human genetics - 1 Jan 2002

Okuda Tomohiko, Fujioka Yoshihiko, Kamide Kei, Kawano Yuhei, Goto Yoichi, Yoshimasa Yasunao, Tomoike Hitonobu, Iwai Naoharu, Hanai Sotaro, Miyata Toshiyuki

Abstract excerpt

Single-nucleotide polymorphisms (SNPs) located in coding regions (coding SNPs; cSNPs) with amino acid substitution can potentially alter protein function. Therefore, identification of the nonsynonymous cSNPs of the genes of common diseases is valuable in tests of association with phenotypes. In this study, we validated 525 candidate cSNPs from 179 hypertension candidate genes deposited in the publicly available...

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PMID: 12181638
DOI: 10.1007/s100380200056

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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