Article
Association study with 33 single-nucleotide polymorphisms in 11 candidate genes for hypertension in Chinese.
Hypertension (Dallas, Tex. : 1979) - 1 Jun 2006
Gu Dongfeng, Su Shaoyong, Ge Dongliang, Chen Shufeng, Huang Jianfeng, Li Biao, Chen Runsheng, Qiang Boqin
Abstract excerpt
Essential hypertension is considered to be a typical complex disease with multifactorial etiology, which leads to inconsistent findings in genetic studies. One possibility of failure to replicate some single-locus results is that the underlying genetics of hypertension are not only based on multiple genes with minor effects but also on gene-gene interactions. To test this hypothesis, a case-control study was...
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