Article
Gender-specific association between the kininogen 1 gene variants and essential hypertension in Chinese Han population.
Journal of hypertension - 1 Mar 2009
Zhao Weiyan, Wang Yaping, Wang Laiyuan, Lu Xiangfeng, Yang Wei, Huang Jianfeng, Chen Shufeng, Gu Dongfeng
Abstract excerpt
BACKGROUND: Kininogens serve as the precursors of potent vasoactive kinin peptides and also function as cysteine proteinase inhibitors. METHOD: Given its potential role in blood pressure homeostasis, a tagging single nucleotide polymorphism (SNP) based case-control study was conducted to explore the association between kininogen 1 gene common variants and essential hypertension in Chinese Han population. Four...
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